Successful control of carbapenem-resistant Acinetobacter baumannii in a Korean university hospital: a 6-year perspective.
نویسندگان
چکیده
BACKGROUND This study evaluated the effect of infection control interventions on the incidence of carbapenem-resistant Acinetobacter baumannii (CRAB) in a tertiary hospital over a 6-year period. METHODS Multiple interventions, including cohorting, promotion of hand hygiene, active surveillance in the intensive care units, and environmental cleaning, were implemented from 2007 through 2009 (period 1). From 2009 through 2012 (period 2), infection control programs were enhanced by the introduction of an onsite education and hand hygiene campaign in preparation for hospital accreditation. To assess the efficacy of the infection control intervention programs, the nosocomial incidence density of CRAB, consumption of alcohol-based hand gel, and consumption of antimicrobials during the study period were measured. RESULTS The incidence density of CRAB increased from 0.35 to 0.46 per 1000 patient-days (PD) during period 1, but decreased to 0.06 per 1000 PD in period 2 (P = .011). The consumption of alcohol-based hand gel increased from 5.6 L to 11.9 L per 1000 PD during the study period (P < .001). There was a significant association between the incidence density of CRAB and carbapenem use (P = .008). CONCLUSIONS Education for infection control programs, hand hygiene campaign, and the judicious use of carbapenem may decrease the nosocomial incidence of CRAB.
منابع مشابه
Nosocomial Outbreak of Carbapenem-Resistant Acinetobacter baumannii in Intensive Care Units and Successful Outbreak Control Program
Acinetobacter baumannii has been increasingly reported as a significant causative organism of various nosocomial infections. Here we describe an outbreak of carbapenem-resistant A. baumannii (CRAB) in the ICUs of a Korean university hospital, along with a successful outbreak control program. From October 2007 through July 2008, CRAB was isolated from 57 ICU patients. Nineteen patients were diag...
متن کاملMolecular epidemiology of carbapenem resistance in Acinetobacter baumannii isolates in Shahid Mohammadi Hospital, Bandar Abbas, Iran
Introduction: Acinetobacter baumannii is a major cause of nosocomial infections which affect mainly disabled patients in intensive care units. The bacteria may acquire resistance to antibiotics and hence can seriously endanger antibiotic therapy. The most important problem facing treatment of A. baumannii is increasing reports of resistance to a wide range of antibiotics, including carbapenems,...
متن کاملPhenotypic and Genotypic Detection of Metallo-Beta-Lactamases in Carbapenem Resistant Acinetobacter baumannii
متن کامل
Clinical outcomes of hospital-acquired infection with Acinetobacter nosocomialis and Acinetobacter pittii.
The role of Acinetobacter nosocomialis and Acinetobacter pittii, which belong to the A. calcoaceticus-A. baumannii complex, in hospital-acquired infections is increasingly recognized. Here we describe a retrospective cohort study of hospital-acquired A. calcoaceticus-A. baumannii complex infections at a university hospital in Thailand. A total of 222 unique cases were identified between January...
متن کاملPrevalence of IMP and SPM Genes in Clinical Isolatesof Carbapenem Resistant Acinetobacter baumannii in Educational Hospitals of Sari, Iran
Background and purpose: Acinetobacter Baumannii is an opportunistic bacterium, which is considered as a concern in hospitals throughout the world due to high antibiotic resistance rate. The aim of this study was to investigate the prevalence of carbapenem resistance genes in clinical isolates of this bacterium. Materials and methods: In this study, 100 clinical isolates of Acinetobacter Bauman...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- American journal of infection control
دوره 42 9 شماره
صفحات -
تاریخ انتشار 2014